Figure 1.

Results from the ALE meta-analysis revealed significantly reduced activation (shown in blue) in the fronto-parietal network (Prefrontal cortex and bilateral Parietal lobe), Insula, and right Parahippocampal cortex (see images at Z = −6, Z = 9, Z = 32, Z = 43, the Z values represent the horizontal coordinates from inferior to superior direction, more negative Z value, more inferior direction and vice versa), but increased activation (shown in yellow and red) in the thalamus (see image at Z = 14) across different attention tasks following total sleep deprivation compared to rested wakefulness. All activations are significant at P < 0.05 corrected for multiple comparisons using the false discovery rate. ALE, activation likelihood estimation; L, left; R, right; B, bilateral.