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. 2015 Feb 1;38(2):305–313. doi: 10.5665/sleep.4420

Figure 4.

Figure 4

Relative weight change calculated as a percentage of the initial weight, in gamma-hydroxybutyrate-treated and control groups (black and gray bars, respectively). (A) Two-way repeated-measures analysis of variance for factors “treatment,” “week” and their interaction, followed by Holm-Sidak post hoc test showed that the weight gain by C57BL/6J mice in the treated group was significantly less compared to the control group; * P < 0.05, N = 20. Lines connect weeks for which significant differences were found. (B) The weight gain in obese (ob/ob) treated group was lower compared to the control group, but not significantly different between the treated and the control group (N = 16). (C) GABAB KO treated mice lost weight compared with the control mice; * P < 0.05, N = 11. GABAB, gamma-aminobutyric acid B; KO, knockout mice.