Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Aug 1;14:279. doi: 10.1186/1472-6882-14-279

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Sui et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

ZJW suppresses P-gp mediated MDR by inhibiting activation of Akt (Ser473)/IκB phosphorylation (Ser473) in vitro . (A&B) Western blotting assay was carried out to detect the level of Akt, phosphorylation of Akt (Thr307/Ser473), IκB, p65, and phosphorylation of IκB in HCT116/L-OHP cells treated with LY294002 (20 μM, 2 h), ZJW (50 μg/mL, 48 h), and a combination of ZJW (50 μg/mL, 48 h) and IGF-1 (100 ng/mL, 48 h). GAPDH was used to ensure equal loading of proteins in each lane. Data are means ± SD of values from triplicate experiments. **P < 0.01 vs. control group.