Table 1. Composition of study cohorts.
| Data Set | Pendergrass | Milano | Hinchcliff | |||||
| SSc | Control | SSc | Control | Morphea | SSc | Control | Morphea | |
| All subjects | N = 22 | N = 9 | N = 24 | N = 6 | N = 3 | N = 34 | N = 11 | N = 1 |
| Age*, mean (SD) | 46.1 (9.1) | NA | 51.8 (10.4) | 40.2 (10.6) | 50.7 (2.9) | 47.7 (11.7) | 41.2 (11.8) | 47 |
| Sex, n (% women) | 17 (77.3) | NA | 21 (87.5) | 5 (83.3) | 3 (100.0) | 32 (94.1) | 7 (63.6) | 1 (100.0) |
| SSc patients only | N = 22 | N = 24 | N = 34 | |||||
| SSc subtype, n (% diffuse) | 22 (100.0) | 17 (70.8) | 31 (91.2) | |||||
| SSc disease duration*, mean (SD) | 18.4 (13.1) mos | 7.7 (7.2) yrs | 52.7 (67.4) mos | |||||
| SSc autoantibody, n (% positive) | ||||||||
| Scl-70 | 3 (13.6) | 5 (20.8) | 9 (26.5) | |||||
| RNA Pol III | 3 (13.6) | NA | 9 (26.5) | |||||
| ACA | 1 (4.5) | 2 (8.3) | 2 (5.9) | |||||
| SSc intrinsic subset, n (%) | ||||||||
| Inflammatory | 9 (40.9) | 5 (20.8) | 17 (50.0) | |||||
| Proliferative | 8 (36.4) | 11 (45.8) | 7 (20.6) | |||||
| Normal-like | 2 (9.1) | 4 (16.7) | 7 (20.6) | |||||
| Limited | NA | 3 (12.5) | 2 (5.9) | |||||