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. Author manuscript; available in PMC: 2015 Jan 10.
Published in final edited form as: Cent Nerv Syst Agents Med Chem. 2012 Jun;12(2):122–130. doi: 10.2174/187152412800792742

Fig. (3).

Fig. (3)

The time courses of [MP] changes following administration. The animal experimental procedures were the same as in Fig. 1, but MPSS (30 mg/kg) was administered (iv). The HPLC analysis method is described in Materials and Methods. a. The time courses of [MP] changes in blood and CSF samples from SCI and sham control rats. A dramatic decline of [MP] in blood samples is shown with a comparatively slower reduction of [MP] in CSF. b. The CSF/blood ratios of [MP] over time in injured and sham control animals, showing greater penetration of the BSB by MP in both injured and sham control animals compared with MnTBAP in Fig. 1b.