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. Author manuscript; available in PMC: 2015 Jan 10.
Published in final edited form as: Pharm Anal Acta. 2014 Sep 29;5:1000311. doi: 10.4172/2153-2435.1000311

Figure 2.

Figure 2

Photomicrographs of a sagittally sectioned foot of a representative CH3 mouse sacrificed 25 days PI with L. mayor and treatment with PBS. Panel A) Moderate chronic inflammation is present in the soft tissues (arrows). The footpad epidermis and haired skin are intact. The inflammation has not spread to the bones. H&E, bar = 500 µm. Panel B) The subcutis has sheets of closely packed mixed mononuclear inflammatory cells with darkly stained lymphocytes and plasma cells in the upper half of the photomicrograph and more lightly stained macrophages in the lower half. These surround a central area of dense collagenous connective tissue. H&E, bar = 50 µm.