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. Author manuscript; available in PMC: 2015 Jan 10.
Published in final edited form as: AIDS. 2013 Oct 23;27(16):2505–2517. doi: 10.1097/01.aids.0000432455.06476.bc

Figure 3. Partial least square discriminant analysis of cytokine profiles following stimulation with TLR Ligands and HIV-1.

Figure 3

A PLSDA score plot (left) indicates 19 cytokine secretion measurements differentiate between TLR (CL097 and ssRNAGag1166) and HIV-1(AT-2 HIV-1 or HIV-1NL43) stimuli (separated by LV1) and also between AT-2 HIV-1 and HIV-1 strain NL-43 stimuli (separated by LV2). A loadings plot (right) illustrates that HIV stimuli (positive scores on LV1) are associated with a profile involving IP-10, IL-2, IL-4, IL-13, and IL-5 compared to TLR stimuli. LV2 (not shown) distinguishes between AT-2 and NL-43 HIV strains.