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. 2014 Dec 16;83(1):324–338. doi: 10.1128/IAI.02494-14

FIG 7.

FIG 7

Comparisons of gene transcription dynamics between and within the granuloma scenarios illustrated in Fig. 3. Only the signal activation interval (δ) parameters are shown, since they are the only significant ones. (A) Comparison of NF-κB signal activation intervals between containment and dissemination. The NF-κB signal activation interval is shorter (less stable) in containment than in dissemination (P < 1e-8). (B) Comparison between the signal activation intervals for the three different pathways in the containment scenario. The NF-κB signal activation interval is shorter (less stable) than the STAT1 interval (P < 8e-6) and the STAT3 interval (P < 0.012). (C) Comparison between signal activation intervals for the three different pathways in the dissemination scenario. The NF-κB signal activation interval is longer (more stable) than the STAT1 interval (P < 2e-3) and the STAT3 interval (P < 0.05).