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Redistribution of telomerase enzyme activity after H2O2 treatment. Telomerase enzyme activity was measured in L. major nuclear, mitochondrion-enriched, and cytoplasmic fractions after exposing cells for 1 h to 10 or 25 μM H2O2. Data are means ± SEMs of three independent measurements. Telomerase activity values for nuclear and mitochondrion-enriched fractions from treated cells show statistically significant difference from untreated cell fractions (analysis of variance [ANOVA]).
