Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Oct 6;53(48):13054–13058. doi: 10.1002/anie.201405664

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

18-Crown-6 binding modes. The upper part of each panel illustrates the structure of the molecule, the lower part is a representation, where dashed lines represent hydrogen bonds and the red semi-circles are hydrophobic contacts. a) In the K-crown binding mode, a single lysine binds the CR axially. b) Hydrophobic and π-orbital containing side-chains interact laterally with CR. No residues interact with the central region of CR, which commonly but not always coordinates two water molecules. Letters in parenthesis indicate the chain ID. c) In the mixed KC-crown binding mode, the CR is coordinated axially by a lysine, while hydrophobic and π-orbital containing side-chains interact with it laterally. Letters in parenthesis indicate the chain ID, with asterisk indicating symmetry equivalents.