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. Author manuscript; available in PMC: 2015 Jan 10.
Published in final edited form as: Mol Cancer Ther. 2013 Sep 12;12(11):2483–2493. doi: 10.1158/1535-7163.MCT-13-0486

Figure 1.

Figure 1

WIN inhibits colon cancer cell growth, induces apoptosis and PARP cleavage. SW480 (A), RKO (B) and HT-29 (C) cells were treated with DMSO and 2.5–7.5 μM WIN for 24 and 48 hr and counted, or treated with DMSO and 7.5 μM of WIN for 9 hr (A and B) and 48 hr (C) and effects on Annexin V (SW480 and RKO) and TUNEL (HT-29) staining was determined. Results are expressed as means ± SE for at least three separate determinations, and significant (p < 0.05) growth inhibition or induction of apoptosis by by WIN is indicated (*). (D) Cells were treated with DMSO and 2.5–7.5 μM of WIN for 48 hr and whole cell lysates were examined for expression of cleaved PARP by western blots. β-Actin served as a loading control for all western blots.