Table 2.
Sites of metastatic disease according to age at time of clinical diagnosis
| Site of metastasis | Age (years) at clinical diagnosis (n = 180) | p | ||
|---|---|---|---|---|
| 49 or younger | 50–64 | 65 or older | ||
| (n = 77) | (n = 71) | (n = 32) | ||
| Lung or pleura | ||||
| No | 14 (18.2%) | 14 (19.7%) | 10 (31.3%) | |
| Yes | 63 (81.8%) | 57 (80.3%) | 22 (68.8%) | 0.29 |
| Bone | ||||
| No | 15 (19.5%) | 26 (36.6%) | 5 (15.6%) | |
| Yes | 62 (80.5%) | 45 (63.4%) | 27 (84.4%) | 0.021 |
| Liver | ||||
| No | 13 (16.9%) | 20 (28.2%) | 18 (56.3%) | |
| Yes | 64 (83.1%) | 51 (71.8%) | 14 (43.8%) | <0.001 |
| Non-axillary nodes | ||||
| No | 37 (48.1%) | 26 (36.6%) | 18 (56.3%) | |
| Yes | 40 (51.9%) | 45 (63.4%) | 14 (43.8%) | 0.14 |
| Adrenal glands | ||||
| No | 35 (45.5%) | 39 (54.9%) | 24 (75.0%) | |
| Yes | 42 (54.5%) | 32 (45.1%) | 8 (25.0%) | 0.019 |
| CNS | ||||
| No | 54 (70.1%) | 59 (83.1%) | 26 (81.3%) | |
| Yes | 23 (29.9%) | 12 (16.9%) | 6 (18.8%) | 0.14 |
| Gynae organs | ||||
| No | 54 (70.1%) | 65 (91.5%) | 30 (93.8%) | |
| Yes | 23 (29.9%) | 6 (8.5%) | 2 (6.3%) | 0.001 |
| Number of metastatic sites | ||||
| 0–3 | 12 (15.6%) | 24 (33.8%) | 17 (53.1%) | |
| 4–5 | 33 (42.8%) | 26 (36.6%) | 8 (25.0%) | |
| 6–13 | 32 (41.6%) | 21 (29.6%) | 7 (21.9%) | 0.002 |