Table 4.

Changes in oestrogen and progesterone receptor status according to site of metastatic disease

Metastatic site (n)	Oestrogen receptor (ER)		Progesterone receptor (PgR)
	Primary versus metastatic status	Significance	Primary versus metastatic status	Significance
Lung or pleura (47)	13 pos to neg	< 0.001	10 pos to neg	0.09
	0 neg to pos		3 neg to pos
	24 neg to neg		15 neg to neg
	10 pos to pos		18 pos to pos
Bone (38)	11 pos to neg	0.022	8 pos to neg	0.039
	2 neg to pos		1 neg to pos
	15 neg to neg		13 neg to neg
	10 pos to pos		16 pos to pos
Liver (32)	10 pos to neg	0.002	8 pos to neg	0.039
	0 neg to pos		1 neg to pos
	18 neg to neg		14 neg to neg
	4 pos to pos		9 pos to pos
Non-axillary nodes (24)	8 pos to neg	0.008	3 pos to neg	0.25
	0 neg to pos		0 neg to pos
	14 neg to neg		13 neg to neg
	2 pos to pos		8 pos to pos

McNemar test.