Table 4.
Age and lifestyle moderating effects (βa and βe) on variance components of CHD
| Men | Women | |||
|---|---|---|---|---|
| Moderating effect on genetic component (95% CI) | Moderating effect on environmental component (95% CI) | Moderating effect on genetic component (95% CI) | Moderating effect on environmental component (95% CI) | |
| Age | 0.31 (0.27, 0.31) | 0.45 (0.41, 0.46) | 0.23 (0.19, 0.24) | 0.45 (0.37, 0.45) |
| Smoking | 0.06 (−0.06, 0.19) | 0.26 (0.12, 0.40) | −0.12 (−0.24, 0.01) | −0.22 (−0.32, −0.10) |
| Sedentary lifestyle | 0.03 (−0.15, 0.25) | −0.10 (−0.29, 0.12) | 0.24 (−0.01, 0.53) | 0.01 (−0.24, 0.30) |
| Alcohol consumption | −0.15 (−0.27, −0.01) | −0.08 (−0.22, 0.07) | 0.12 (−0.32, 0.36) | −0.34 (−0.55, 0.06) |
| BMI | 0.07 (0.03, 0.11) | 0.26 (0.20, 0.33) | 0.05 (0.00, 0.09) | 0.33 (0.24, 0.38) |
CI, confidence interval; BMI, body mass index.
Moderating effect on genetic component is βa, and moderating effect on environmental component is βe.