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. 2014 Dec 4;15(1):1065. doi: 10.1186/1471-2164-15-1065

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© Silva et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Protein-protein interactions. Protein-protein interactions of the proteins identified in DETA/NO-exposed cells. Exclusive proteome, circle; up-regulated, square; and down-regulated, rhombus. The sizes of the nodes represent the degree of interaction for each gene/protein; the major nodes demonstrate greater interactions. The colors of nodes and lines are in an increasing gradient scale from yellow to green to blue. The networks were visualized using Cytoscape.