Table 4.
Effect of the fractions of methanolic root extract of Dodonaea angustifolia on the body weight of the mice
| Test substance | Dose (mg/kg) | Body weight (kg) | %change | |
|---|---|---|---|---|
| D-0 | D-4 | |||
| Butanol | 200 | 30.42 ± 0.68 | 29.18 ± 0.21 | -4.25c |
| 400 | 29.84 ± 0.99 | 28.66 ± 0.44 | -4.11c | |
| 600 | 28.70 ± 1.06 | 27.60 ± 0.34 | -3.98a | |
| Chloroquine | 10 | 29.42 ± 2.17 | 29.04 ± 1.63 | -1.30 |
| Distilled water | 1 ml | 28.72 ± 0.77 | 25.74 ± 0.45 | -11.58 |
| Chloroform | 200 | 29.74 ± 1.46 | 27.80 ± 1.92 | -6.98 |
| 400 | 29.50 ± 1.75 | 27.06 ± 0.83 | -9.02 | |
| 600 | 29.56 ± 1.81 | 27.20 ± 1.10 | -8.68 | |
| Chloroquine | 10 | 29.38 ± 1.04 | 29.36 ± 1.32 | -0.07 |
| Distilled water | 1 ml | 30.34 ± 0.92 | 26.54 ± 1.39 | -14.32 |
| Aq. fraction | 200 | 30.26 ± 1.30 | 28.18 ± 0.64 | -7.38 |
| 400 | 30.98 ± 0.93 | 28.34 ± 0.42 | -9.31 | |
| 600 | 29.40 ± 2.32 | 27.36 ± 0.46 | -7.46 | |
| Chloroquine | 10 | 28.84 ± 1.39 | 28.46 ± 2.24 | -1.34 |
| Distilled water | 1 ml | 31.46 ± 0.83 | 27.06 ± 0.79 | -16.26 |
a = P < 0.05, c = P < .001, Body weight expressed as mean ± SD, n = 5 the results are expressed as the percent reduction of body weight with reference to day 0. Distilled water = control, D0 = a day infection initiated, D4 = 5th day of infection.