TABLE IV.
Expression quantitative trait loci in IL1RL1 associated with ST2L mRNA levels
Allele frequency | P value (odds ratio) | ||||||||
---|---|---|---|---|---|---|---|---|---|
rsID | Location | MAF | n | Genotype | HI (n) | LO (n) | Overall | Dominant model | Recessive model |
12712135 | Intron of ST2L mRNA | 0.44 | 49 | AA = 24.5% | 6 | 6 | .07 | .25 | .048 (5.2) |
GA = 53.1% | 5 | 21 | |||||||
GG = 22.4% | 1 | 10 | |||||||
1041973 | Missense A to E ST2L and sST2 position 78 | 0.288 | 52 | AA = 7.7% | 1 | 3 | .02 | .02 (.15) | 1.00 |
AC = 34.6% | 1 | 17 | |||||||
CC = 57.7% | 12 | 18 | |||||||
10185897 | Intron in ST2L mRNA | 0.142 | 49 | AA = 2.0% | 0 | 1 | .03 | 1.00 | .01 (n/a) |
AC = 26.5% | 0 | 13 | |||||||
CC = 71.4% | 12 | 23 |
Statistical analysis was performed using Pearson χ2 test or Fisher exact test, as appropriate.
N/a indicates that an odds ratio could not be calculated due to a 0 value.
MAF, Minor allele frequency.