TABLE V.

Expression quantitative trait loci in IL1RL1 associated with sST2 BAL levels

			Allele frequency				P value (odds ratio)
rsID	Location	MAF	n	Genotype	HI (n)	LO (n)	Overall	Overall Dominant model	Recessive model
10178436	5′ of IL1RL1	0.441	46	CC = 21.7%	1	10	<.0001	.0009 (n/a)	<.0001 (n/a)
				TC = 56.5%	15	11
				TT = 21.7%	10	0
11685424	5′ of IL1RL1	0.458	46	AA = 21.7%	0	10	<.0001	<.0001 (n/a)	.0009 (n/a)
				GA = 56.5%	15	11
				GG = 21.7%	10	0
12712135	Intron of ST2L mRNA	0.44	36	AA = 22.2%	8	0	.0001	.001 (n/a)	.005 (n/a)
				GA = 58.3%	12	9
				GG = 19.4%	0	7
1420089	Intron of ST2L mRNA	0.102	46	AA = 78.2%	16	20	.02	.35	.01 (11.3)
				GA = 19.6%	8	1
				GG = 2.2%	1	0
1041973	Missense A to E ST2L and sST2 position 78	0.288	41	AA = 7.3%	0	3	.02	.02 (.18)	.06
				AC = 29.3%	5	3
				CC = 63.4%	19	7
1420101	Intron in both ST2L and sST2 mRNA	0.371	46	AA = 10.9%	0	5	.02	.14	.01 (n/a)
				GA = 47.8%	12	10
				GG = 41.3%	13	6
17696376	Intron in ST2L mRNA	0.074	36	CC = 80.6%	13	16	.01	1.0	.01 (n/a)
				CT = 16.7%	6	0
				TT = 2.8%	1	0
1921622	Intron in ST2L mRNA	0.411	46	AA = 10.9%	0	5	.03	.01 (n/a)	.36
				AG = 52.1%	14	10
				GG = 37.0	11	6
10185897	Intron in ST2L mRNA	0.142	36	AA = 2.8%	0	1	.04	.44	.03 (.18)
				AC = 27.8%	3	7
				CC = 69.4%	17	8
13015714	3′ of IL1RL1	0.27	46	GG = 6.5%	3	0	.01	.24	.02 (5.1)
				GT = 52.2%	16	8
				TT = 41.3%	6	13

N/a indicates that an odds ratio could not be calculated due to a 0 value.

MAF, Minor allele frequency