Figure 5. Plasma cholesterol and serum ALT levels in heterozygous LDLR-deficient monkey treated by an optimal procedure.
Monkey #19269 was treated with a single injection of HDAd-LDLR at a dose of 1×1012 vp/kg while the balloon was inflated. (a) Plasma cholesterol level. Plasma cholesterol level was 10.40 mmol/l (402 mg/dl) before gene transfer. (b) Serum ALT levels. Normal range (5-61 IU/l) is shown by filled area.