Table 1.
Pathways enriched in gene expression comparisons between groups and diet
| KEGG Pathway | Count | Fold Enrichment | FDR |
|---|---|---|---|
| SS/Mcw, C0.4, vs. SS/Crl, G0.75 | |||
| rno04640:Hematopoietic cell lineage | 26 | 4.0 | 1.88E-06 |
| rno04610:Complement and coagulation cascades | 17 | 2.9 | 1.90E-01 |
| rno04662:B cell receptor signaling pathway | 16 | 2.5 | 1.36E+00 |
| rno04650:Natural killer cell mediated cytotoxicity | 19 | 2.3 | 1.65E+00 |
| rno05340:Primary immunodeficiency | 10 | 3.5 | 1.75E+00 |
| rno04666:Fc gamma R-mediated phagocytosis | 17 | 2.3 | 2.68E+00 |
| rno04060:Cytokine-cytokine receptor interaction | 29 | 1.8 | 4.12E+00 |
| rno04660:T cell receptor signaling pathway | 19 | 2.1 | 4.38E+00 |
| SS/Mcw, C4.0, vs. SS/Crl, C4.0 | |||
| rno00280:Valine, leucine and isoleucine degradation | 21 | 4.8 | 1.54E-06 |
| rno04670:Leukocyte transendothelial migration | 29 | 2.7 | 2.22E-03 |
| rno00071:Fatty acid metabolism | 15 | 3.8 | 2.07E-02 |
| rno04710:Circadian rhythm | 8 | 6.5 | 8.28E-02 |
| rno04610:Complement and coagulation cascades | 17 | 2.6 | 7.88E-01 |
| rno00640:Propanoate metabolism | 11 | 3.5 | 8.03E-01 |
| rno03320:PPAR signaling pathway | 17 | 2.5 | 9.30E-01 |
| rno04920:Adipocytokine signaling pathway | 16 | 2.5 | 1.45E+00 |
| rno05210:Colorectal cancer | 18 | 2.3 | 1.51E+00 |
| rno04514:Cell adhesion molecules (CAMs) | 27 | 1.9 | 1.59E+00 |
| rno04110:Cell cycle | 24 | 2.0 | 1.76E+00 |
| rno04640:Hematopoietic cell lineage | 17 | 2.3 | 2.66E+00 |
| rno04510:Focal adhesion | 32 | 1.7 | 3.04E+00 |
| rno04666:Fc gamma R-mediated phagocytosis | 18 | 2.2 | 3.81E+00 |
| SS/Mcw, C0.4 vs. C4.0 | |||
| rno00480:Glutathione metabolism | 14 | 6.6 | 1.02E-04 |
| rno00380:Tryptophan metabolism | 13 | 7.1 | 1.38E-04 |
| rno00982:Drug metabolism | 15 | 4.9 | 1.55E-03 |
| rno00280:Valine, leucine and isoleucine degradation | 9 | 4.6 | 6.89E-01 |
| rno00350:Tyrosine metabolism | 7 | 4.9 | 3.10E+00 |
| rno03320:PPAR signaling pathway | 10 | 3.3 | 3.24E+00 |
| rno00340:Histidine metabolism | 6 | 5.9 | 3.31E+00 |
| rno00980:Metabolism of xenobiotics by cytochrome P450 | 9 | 3.5 | 4.00E+00 |
| SS/Crl, G0.75 vs. C4.0 | |||
| rno04710:Circadian rhythm | 6 | 21.3 | 5.35E-03 |
| rno00980:Metabolism of xenobiotics by cytochrome P450 | 7 | 5.4 | 1.89E+00 |
| rno04115:p53 signaling pathway | 7 | 4.9 | 3.08E+00 |
| rno00480:Glutathione metabolism | 6 | 5.5 | 4.57E+00 |