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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2014 Nov 21;135(1):31–42. doi: 10.1016/j.jaci.2014.10.015

Figure 2. Moving toward a systems biology view of asthma and allergic diseases.

Figure 2

The colored circular nodes represent genetic, regulatory, metabolite, and environmental entities associated with asthma and allergic disorders. Their identification and potential connectivity can be assessed by the profiling represented in the large rectangular nodes. Green rectangular nodes represent diseases of interest. Orange lines (edges) denote evidence for associations between the implicated nodes in asthma and allergy, many of which are reviewed in this article. Dashed blue edges denote relationships that are currently less well-studied. Examination of the network’s collective nodes and edges, or a substantial subset thereof, would move us toward a systems biology understanding of asthma and allergy.