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. 2014 Nov 15;13:428. doi: 10.1186/1475-2875-13-428

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© Teboh-Ewungkem et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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No movement - effect of IPT coverage. Model results without movement, p ₁₂ = p ₂₁ = 0, showing the effect of increasing IPT coverage with SP on the percent increase of R1 relative to RS and R2 relative to R1 resistance. Graph (a) represents the rate of spread (in percent) of R1 relative to RS parasites, while graph (b) represents that of R2 relative to R1. The parameter p ₁₂ is the rate of movement from the high malaria transmission area to the low transmission area, and p ₂₁ is the rate from the low transmission area to the high transmission area.