Table 6.
Codeml selection analysis using the beta (M7) and the beta plus selection (M8) models
| Toxins | n /model | M0: w | M7:-lnL | M8: beta w/positive selection | -lnL | P |
|---|---|---|---|---|---|---|
| SVMP-MP | 18 | 1.15 | 4,097.97 | p: (0.75, 0.25) | 4,036.79 | 2.7×10−27 |
| GTR+G | w: 3.78 | |||||
| SVMP-DIS | 18 | 1.29 | 1,389.94 | p: (0.84, 0.16) | 1,357.74 | 1.0×10−14 |
| HKY+G | w: 3.29 | |||||
| SVMP-ACR | 18 | 1.39 | 2,197.91 | p: (0.77, 0.23) | 2,133.66 | 1.2×10−28 |
| HKY+G | w: 5.97 | |||||
| 3FTx | 11 | 1.78 | 1,300.92 | p: (0.60, 0.40) | 1,269.86 | 3.2×10−14 |
| SYM+G | w: 6.64 | |||||
| CTL | 12 | 0.53 | 3,913.45 | p: (0.79, 0.21) | 3,892.88 | 1.2×10−9 |
| K80+I+G | w: 2.57 | |||||
| Ficolin | 7 | 0.37 | 4,468.63 | p: (0.99, 0.01) | 4,456.99 | 8.8×10−6 |
| GTR+G | w: 43.40 |
Abbreviations: SVMP–snake venom metalloproteinase, MP–metalloproteinase domain, DIS–disintegrin domain, ACR–cysteine-rich domain, 3FTx–three-finger toxin, CTL–C-type lectin, w–ratio of nonsynonyous to synonymous substitution rates, lnL–log likelihood, n–number of sequences.