Table 1.
Main characteristics of colorectal cancer cases and controls
| Controls (n = 252) | Cases (n = 224) | P value | |
|---|---|---|---|
| n (%) | n (%) | ||
| Male gender | 144 (57) | 137 (61) | 0.37 |
| Median age (years) [IQR] | 66.4 [58.4-74.8] | 69.6 [60.6-75.9] | 0.04 |
| Median current BMI (kg/m2) [IQR] | 26.9 [24.2-30.4] | 25.9 [23.3-29.8] | 0.05 |
| Median Waist/Hip ratio [IQR] | 0.93 [0.88-1.00] | 0.95 [0.89-1.01] | 0.12 |
| Recent weight loss ≥5 kg | 30 (12) | 53 (24) | <0.001 |
| Severe denutrition | 6 (2) | 15 (7) | 0.02 |
| Family history of colorectal cancer | 0.06 | ||
| No | 220 (87) | 178 (79) | |
| Yes | 22 (9) | 29 (13) | |
| Unknown | 10 (4) | 17 (8) | |
| Smoking | 0.72 | ||
| Never smoker | 113 (45) | 107 (48) | |
| Ex smoker | 103 (41) | 89 (40) | |
| Current smoker | 37 (15) | 28 (13) | |
| Alcohol consumption | 0.08 | ||
| None | 47 (19) | 39 (18) | |
| <5 drinks/week | 105 (42) | 74 (33) | |
| ≥5 drinks/week | 98 (39) | 109 (49) | |
| Physical activity | 0.29 | ||
| Low | 65 (26) | 70 (31) | |
| Medium | 139 (55) | 108 (48) | |
| High | 48 (19) | 46 (21) | |
| Type 2 diabetes | 40 (16) | 49 (22) | 0.09 |
| Median HOMA-IR | 0.81 [0.42-1.98] | 0.92 [0.44-2.15] | 0.28 |
| Median pre-albumin (g/L) | 0.26 [0.22-0.30] | 0.23 [0.19-0.28] | <0.001 |
| Aspirin or NSAID use in the last month | 51 (20) | 52 (23) | 0.43 |
| Statin use in the last month | 60 (24) | m 69 (31) | 0.09 |
| TNM stage | |||
| (Tis) | 13 (5.8) | ||
| Stage I | 57 (25.4) | ||
| Stage II | 77 (34.4) | ||
| Stage III | 60 (27.1) | ||
| Stage IV/unstaged | 17 (7.6) |