Table 3.
Cox regression model for multivariate analyses of prognostic factor in MBs
| Variable | Hazard ratio | 95% confidence interval | Pvalue |
|---|---|---|---|
| Age (≤3 years versus >3 years) | 0.396 | 0.140 to 1.118 | 0.080 |
| Gender (male versus female) | 1.421 | 0.485 to 4.160 | 0.521 |
| WHO histological subtype (classic versus desmoplastic) | 0.931 | 0.308 to 2.808 | 0.899 |
| Tumor location (fourth ventricle versus outside fourth ventricle) | 1.201 | 0.404 to 3.573 | 0.741 |
| Residual tumor size (≤1.5 cm2 versus >1.5 cm2) | 0.391 | 0.139 to 1.102 | 0.075 |
| Metastatic status (M0 versus M1) | 1.720 | 0.310 to 9.546 | 0.534 |
| Tumor risk (standard versus high) | 0.695 | 0.041 to 11.92 | 0.802 |
| Differentiation (differentiated versus undifferentiated) | 0.348 | 0.121 to 0.998 | 0.050 |
| MIB-1 index (low versus high) | 5.949 | 1.986 to17.814 | 0.001 |
| DJ-1 expression (low versus high) | 4.531 | 1.443 to14.223 | 0.009 |
| p-Akt expression (low versus high) | 0.765 | 0.217 to 2.698 | 0.678 |