Table 5.
Detected LAP gene cluster
| Phylum | Locus Tag of dehydrogenase | Similar to † | Reference # | |
|---|---|---|---|---|
| Clostridium botulinum A2 BoNT/A2 Kyoto-F | Firmicutes | CLM_0573 | clostridiolysin S | |
| Clostridium botulinum A BoNT/A1 ATCC 19397 | Firmicutes | CLB_0528 | clostridiolysin S | |
| Clostridium botulinum A BoNT/A1 Hall | Firmicutes | CLC_0561 | clostridiolysin S | |
| Clostridium botulinum BoNT/B1 Okra | Firmicutes | CLD_0261 | clostridiolysin S | |
| Clostridium botulinum BoNT/A3 Loch Maree | Firmicutes | CLK_3698 | clostridiolysin S | |
| Clostridium botulinum Ba4 str. 657 | Firmicutes | CLJ_B0564 | clostridiolysin S | |
| Clostridium botulinum F230613 | Firmicutes | CBF_0535 | clostridiolysin S | |
| Clostridium botulinum H04402 065 | Firmicutes | H04402_00508 | clostridiolysin S | |
| Clostridium botulinum A ATCC 3502 | Firmicutes | CBO0487 | clostridiolysin S | [50] |
| Clostridiumbotulinum F str. Langeland | Firmicutes | CLI_0567 | clostridiolysin S | |
| Thermoanaerobacter mathranii mathranii A3, DSM 11426 | Firmicutes | Tmath_0475 | ** | |
| Brachyspira hyodysenteriae WA1 | Spirochaetes | BHWA1_02354 | ||
| Brachyspira pilosicoli 95/1000 | Spirochaetes | BP951000_0919 | * | |
| Brachyspira intermedia PWS/A | Spirochaetes | Bint_2324 | * | |
| Brachyspira murdochii 56–150, DSM 12563 | Spirochaetes | Bmur_0997 | * |
*All strains share an identical precursor peptide sequence; **no precursor peptide could be annotated; †Cluster shows similarities to characterized RiPP cluster; #Cluster was previously detected by genome mining approaches.