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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Biochim Biophys Acta. 2014 Nov 13;1853(2):370–376. doi: 10.1016/j.bbamcr.2014.11.003

Figure 5. Caspases inhibitors further suppress Runx2 promoter activity by inhibiting degradation of HDAC4.

Figure 5

(A) Promoter assay showed that inhibition of Runx2 promoter activity presents an HDAC4-dose-dependent manner in chondrocytes. (B) HDAC4 inhibition of Runx2 promoter could be enhanced by caspases inhibitors via suppressing degradation of HDAC4.