Table 8.

Other surgery types

Surgery type	Author and year	Comparator and patients per arm (n)	Primary endpoint	Principal results
Gynaecologic surgery	Angioli 2009 [23]	Floseal® (8)	Control of minor bleeding	Not significant differences in the time to haemostasis, blood loss, or the operating time.
		Control (bipolar forceps or carbon-dioxide laser) (12)
	Raga 2009 [24]	Floseal® (25)	Haemostatic efficacy	Less intra- and postoperative blood loss (p = 0.001) and a lower rate of transfusions (0% in the Floseal® group) (p < 0.001) for patients treated with Floseal®. A shorter length of hospital stay in the Floseal® group (p = 0.005).
		Isotonic sodium chloride (25)
	Sönmezer 2013 [25]	Floseal® (13)	Ovarian reserve and damage	During the first postoperative month, ovarian damage was significantly lower in the Floseal® group (p < 0.001). However, at the third month after surgery, NS differences were found.
		Bipolar electrosurgical coagulation (15)
Lacrimal surgery	Durrani 2007	Floseal® (10)	Postoperative bleeding and patient comfort	Nine patients in the Floseal® group had no or minimal bleeding; this finding was statistically significant at all three measured time points (immediately (p = 0.047), at 12 h (p = 0.006), and at 24 h after surgery (p = 0.005)). The Floseal® group also had less postoperative discomfort (p = 0.0001).
		Without Floseal® (10)
Thyroid surgery	Testini 2009 [22]	Floseal® (54)	Operating time and wound drain removal	A significantly shorter operating time in the Floseal® group than in the other groups (p < 0.05). More rapid wound drain removal and a shorter length of hospital stay in the Floseal® group compared with the other groups (p < 0.05 both). Not significant difference in postoperative morbidity.
		Surgical haemostasis (49)
		Tabotamp (52)