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. Author manuscript; available in PMC: 2015 Jan 11.
Published in final edited form as: Am J Transplant. 2014 Apr 7;14(5):1061–1072. doi: 10.1111/ajt.12674

Figure 9. In CsA-treated animals, transfusion-associated ABMR correlated with greater inflammation and M1 macrophage phenotype.

Figure 9

Transfusion-induced ABMR in rats was associated with inflammation (iNOS, Nox2) and M1 (iNOS, IRF5) macrophage phenotype. Complement regulatory proteins (Crry, DAF) were not significantly affected by transfusion. ABMR, antibody-mediated rejection; CsA, cyclosporine A; iNOS, inducible nitrogen oxide synthase; IRF5, interferon regulatory factor 5; Nox2, NADPH oxidase 2.