Skip to main content
. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Cancer Prev Res (Phila). 2014 Nov 17;8(1):77–85. doi: 10.1158/1940-6207.CAPR-14-0245

Figure 2.

Figure 2

Incidences of bronchial preneoplastic lesions and LSCC in mice treated with NTCU or NTCU + LPS and inhibitory effects of DIM on LSCC development. As mouse LSCC does not form visible solid nodules on the surface of the lung, serial tissue sections were made from each formalin-fixed lung and 1 in every 20 sections was stained with H&E. To assess specific effects of the different treatments on each histopathologic stage, all of the bronchioles in each given slide were counted and grouped into 5 categories based on normal, hyperplasia, metaplasia, carcinoma in situ (dysplasia was included in this category), and invasive SCC. The number in each category was then converted into percentage. *, P < 0.05, compared to NTCU group; *, P < 0.05, compared to NTCU group; # P < 0.05, NTCU/LPS vs NTCU/LPS/DIM.