Table 2.

Metabolites whose change is significantly correlated to the change in tissue Cyclin D1 expression (53 metabolites P≤0.05; 23 metabolites Q≤0.10).

Lysolipids	P-value	Q-value	R2
1-palmitoylglycerophosphocholine	<0.001	0.01	0.62
1-palmitoleoylglycerophosphocholine	<0.001	0.02	0.59
1-stearoylglycerophosphocholine	<0.001	0.01	0.61
2-stearoylglycerophosphocholine	<0.001	0.01	0.61
1-oleoylglycerophosphocholine	<0.001	0.01	0.62
1-eicosadienoylglycerophosphocholine	<0.001	0.01	0.63
2-oleoylglycerophosphocholine	<0.01	0.05	0.55
2-linoleoylglycerophosphocholine	0.01	0.09	0.51
1-eicosatrienoylglycerophosphocholine	0.01	0.09	0.50
1-heptadecanoylglycerophosphocholine	0.01	0.09	0.49
1-palmitoylplasmenylethanolamine	0.02	0.14	0.42
Acylcarnitines
palmitoylcarnitine	<0.001	0.01	0.63
oleoylcarnitine	<0.001	0.02	0.59
decanoylcarnitine	0.01	0.10	0.47
butyrylcarnitine	0.02	0.14	0.43
acetylcarnitine	0.02	0.14	0.43
Amino Acids and Metabolites
indolelactate	0.01	0.09	0.49
kynurenine	0.01	0.10	0.47
alpha-hydroxyisocaproate	0.01	0.10	0.47
phenylalanylserine	0.01	0.10	0.47
serine	0.01	0.11	0.46
phenol sulfate	0.02	0.12	0.45
3-indoxyl sulfate	0.02	0.14	0.43
alanine	0.02	0.14	0.43
asparagine	0.03	0.16	0.41
aspartate	0.04	0.17	0.39
gamma-glutamylvaline	0.04	0.17	0.39
symmetric and asymmetric dimethylarginine (SDMA + ADMA)	0.04	0.18	0.39
Glucose/Energy Metabolism
1,5-anhydroglucitol (1,5-AG)	0.01	0.09	0.50
Fatty Acids
3-carboxy-4-methyl-5-propyl-2-furanpropanoate (CMPF)	0.01	0.03	0.57
15-methylpalmitate	0.01	0.10	0.48
cis-vaccenate (18:1n7)	0.02	0.12	0.45
palmitoyl sphingomyelin	0.02	0.14	0.42
adrenate (22:4n6)	0.03	0.16	0.41
17-methylstearate	0.03	0.17	0.40
palmitate, methyl ester	0.04	0.17	0.39
oleate (18:1n9)	0.04	0.19	0.38
Other
bilirubin (E,E)	<0.001	0.01	0.65
N1-methyladenosine	<0.01	0.05	0.53
quinate	0.01	0.09	0.49
2-ethylhexanoate	0.02	0.14	0.43
pregnendiol disulfate	0.02	0.15	0.42
erythritol	0.03	0.16	0.41
bilirubin (Z,Z)	0.03	0.17	0.40
urate	0.04	0.17	0.39
cholesterol	0.04	0.19	0.38
alpha-tocopherol	0.04	0.19	0.38