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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Cancer Prev Res (Phila). 2014 Nov 3;8(1):27–36. doi: 10.1158/1940-6207.CAPR-14-0193

Figure 6. Effects of carvedilol on human lung tumor A549 growth and migration in vitro and in vivo.

Figure 6

(A) The β-blocker carvedilol was examined for effects on soft agar assay (in black) and SRB assay (in gray) and data were normalized to their respective controls and plotted together; asterisk (*) and cross (†) indicates the soft agar and SRB assay is statistically different than control, respectively, (p < 0.05) as determined by ANOVA with Tukey-Kramer post hoc test. (B) Cell migration of A549 cells was quantified by the gap distances before and after 24 hour treatment with carvedilol; asterisk (*) indicates that the 24 hour period was statistically different than the initial (p < 0.05) as determined by paired t-test, n = 3. (C) Effect of carvedilol on xenograft lung tumor growth in mice. Asterisk (*) indicates p-value is < 0.05 between the two points as determined via a RM-ANOVA with a Newman-Keuls multiple-comparison post hoc test; n ≥ 4.