Table 2.
Association between DPA1-DPB1 Heterodimers and Narcolepsy in Stepwise Analysis
| HLA-DPA1-DPB1 Heterodimer | No. of Control Subjects (Freq) | No. of Case Subjects (Freq) |
Mantel-Haenszel Test |
||
|---|---|---|---|---|---|
| OR (CI) | p | p Heterogeneity Test | |||
| 01:03-04:02 | 160 (0.15) | 88 (0.083) | 0.51 (0.38–0.67) | 1.01 × 10−06 | 0.852 |
| 01:03-04:01 | 516 (0.58) | 459 (0.52) | 0.61 (0.47–0.80) | 2.07 × 10−04 | 0.342 |
| 02:02-19:01 | 7 (0.020) | 0 (0.00) | 0 (0.00–NA) | 0.008 | NA |
| 02:02-05:01 | 193 (0.57) | 218 (0.64) | 1.41 (1.02–1.95) | 0.039 | 0.387 |
The p values were calculated with the chi-square test and Maentel-Haenszel test. The p heterogeneity test is Breslow-Day’s p value. Abbreviations are as follows: CI, confidence interval; Freq, carrier frequency; NA, not available (the exact OR or p value could not be calculated); and OR, odds ratio.