Table V.
Environmental and host risk factors associated with asthma phenotypes among dental healthcare workers in multivariate regression models
| Characteristics | Asthma Phenotypes, OR (95% CI)
|
||
|---|---|---|---|
| Prevalence (%) (N = 421) | Atopic asthma (6.9%) n = 29 | Non-atopic asthma (5.9%) n = 25 | Work-exacerbated asthma (4.0%) n = 17 |
| Atopy | n/a | n/a | 3.40 (1.07 – 10.83)* |
| Asthma history | |||
| - Family history of asthma | 1.89 (0.68 – 5.24) | 1.20 (0.24 – 5.99) | 1.94 (0.54 – 7.03) |
| - Childhood-onset asthma (< 17 years) | 0.63 (0.17 – 2.34) | 1.11 (0.98 – 1.26) | 0.26 (0.06 – 1.09) |
| - Number of asthma attacks in past 12 months | 0.39 (0.11 – 1.30) | 6.43 (0.57 – 72.05) | 0.70 (0.23 – 2.16) |
| Past medical history | |||
| - Pneumonia | 3.47 (1.17 – 10.33)* | 2.42 (0.64 – 9.17) | 15.86 (5.14 – 48.94)** |
| - Tuberculosis | 2.19 (0.249 – 19.30) | 1.05 (1.01 – 1.09)* | 2.02 (0.23 – 17.99) |
| - Recent chest infections | 0.71 (0.23 – 2.15) | 0.94 (0.30 – 2.99) | 1.26 (0.38 – 4.12) |
| Upper airway symptoms | |||
| - Ocular-nasal symptoms | 4.43 (1.92 – 10.25)** | 0.58 (0.19 – 1.79) | 5.88 (1.94 – 17.81)* |
| - Work-related ocular-nasal symptoms | 1.85 (0.70 – 4.89) | 0.99 (0.28 – 3.54) | 6.70 (2.35 – 19.13)** |
| Occupational exposures | |||
| - Student versus staff status | 0.62 (0.19 – 2.01) | 1.73 (0.37 – 8.16) | 0.84 (0.16 – 4.39) |
| - Spray, mist or steam at work | 5.11 (0.52 – 50.23) | 9.57 (0.21 – 426) | 4.48 (0.44 – 45.31) |
| - Regular use of PPE | 0.73 (0.19 – 2.76) | 0.23 (0.08 – 0.68)* | 0.45 (0.13 – 1.56) |
| - Glove versus no glove use | 0.39 (0.17 – 0.89)* | 0.61 (0.23 – 1.61) | 0.74 (0.25 – 2.22) |
| - Latex versus non-latex glove use | 0.72 (0.32 – 1.60) | 0.78 (0.31 – 1.96) | 1.68 (0.59 – 4.81) |
| - Respiratory protection (surgical mask) versus no respiratory protection | 0.39 (0.17 – 0.89)* | 0.61 (0.23 – 1.61) | 0.74 (0.25 – 2.22) |
| Employment duration (≤ 10 years as baseline) | |||
| - 11 – 20 years | 1.70 (0.48 – 5.96) | 0.35 (0.07 – 1.82) | 0.61 (0.11 – 3.37) |
| - > 20 years | 1.92 (0.45 – 8.17) | 1.53 (0.43 – 5.39) | 1.99 (0.46 – 8.70) |
| Allergic sensitization | |||
| - Sensitization to composite latex (k82) extract | 1.49 (0.47 – 4.69) | 1.04 (1.01 – 1.08)* | 0.78 (0.10 – 6.39) |
| - True latex sensitization | 1.58 (0.43 – 5.81) | 1.04 (1.01 – 1.08)* | 1.22 (0.15 – 10.10) |
Each OR is derived from a separate model adjusted for age, sex, smoking.
*
< 0.05;
**
< 0.001.