Table 5. Systematic review of safety of transepithelial (TE) corneal collagen crosslinking.
| Lead Author | Year | Eyes at latest follow-up (n) | Latest follow-up (months) | Failure to re-epithelialise (%) | Stromal oedema (%) | Sterile infiltrate (%) | Golden striae (%) | Haze (%) | Scar (%) | Infection (%) | Loss of CDVA (%) | ECC change (/mm2) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caporossi A72 | 2013 | 26 | 24 | n/a | — | — | — | — | — | — | — | — |
| Filippello M29 | 2012 | 20 | 18 | n/a | — | — | — | 0 (0 of 20 eyes) | 0 (0 of 20 eyes) | 0 (0 of 20 eyes) | — | −34 (at 1.5 years) |
| Koppen C27 | 2012 | 37 | 12 | n/a | — | — | — | 0 (0 of 37 eyes) | 0 (0 of 37 eyes) | 0 (0 of 37 eyes) | 0 (0 of 37 eyes) | — |
| Leccisotti A30 | 2010 | 51 | 12 | n/a | — | — | — | 4 (2 eyes 51) | 0 (0 of 51 eyes) | 0 (0 of 51 eyes) | 0 (0 of 51 eyes) | +27 (at 1 year) |
| Mastropasqua L36 | 2013 | 20 | 12 | — | 0 | — | — | — | — | — | — | No significant change |
| Stojanovic A28 | 2012 | 61 | 12 | n/a | — | — | — | 0 (0 of 61 eyes) | 0 (0 of 61 eyes) | 0 (0 of 61 eyes) | — | −130 (at 1 year) |
Abbreviations: CDVA, corrected distance visual acuity; ECC, endothelial cell count.
— indicates data not provided in published article.