Table 1. Comparison of baseline characteristics of four regimens, (N=36).
| Baseline variable | 0.5 mg monthly Mean (SD) aMedian | 0.5 mg PRN Mean (SD) aMedian | 2.0 mg monthly Mean (SD) aMedian | 2.0 mg PRN Mean (SD) aMedian | P values (entire study group) |
|---|---|---|---|---|---|
| Age | 82.00 (6.20) | 84.00 (6.00) | 77.25 (6.24) | 74.64 (9.44) | 0.051 |
| Gender | Male: 0 Female: 6 | Male: 1 Female: 6 | Male: 5 Female: 7 | Male: 4 Female: 7 | 0.21 |
| RE vs LE | RE: 3, LE: 3 | RE: 5, LE: 2 | RE: 10, LE: 2 | RE: 6, LE: 5 | 0.38 |
| Cataract: | |||||
| Cort | 3.00a | 2.00a | 1.00a | 0a | 0.24 (Cort) |
| NS | 2.00 | 2.00 | 3.00 | 3.00 | 0.02 (NS) |
| PSC | 0 | 0 | 0 | 0 | 0.70 (PSC) |
| SRF | 1.50a | 1.00a | 2.00a | 1.00a | 0.64 |
| CME | 1.00a | 1.00a | 0a | 0a | 0.15 |
| BCVA (LS) | 54.00 (6.63) | 53.29 (14.35) | 61.50 (7.21) | 58.45 (8.35) | 0.22 (LS) |
| CNV GLD | 2763.28 (602.58) | 2790.51 (1836.77) | 1153.04 (751.54) | 1858.03 (890.12) | 0.083 |
| CNV SA | 3.35 (1.30) | 5.15 (4.57) | 1.06 (1.52) | 1.85 (1.66) | 0.061 |
| PED GLD | 4121.90 (437.70) | 4372.49 (450.46) | 4315.29 (1343.04) | 3619.75 (1498.83) | 0.47 |
| Contrast sensitivity | 24.20 (5.76) | 27.00 (3.10) | 25.73 (7.32) | 27.10 (5.82) | 0.67 |
| PED SA | 9.48 (1.35) | 12.26 (3.72) | 11.46 (7.52) | 8.61 (7.07) | 0.57 |
| PED height | 375.72 (198.27) | 426.30 (149.59) | 501.97 (197.71) | 368.83 (145.55) | 0.29 |
| Central 1-mm thickness | 281.17 (70.91) | 336.57 (113.37) | 311.17 (75.01) | 297.45 (83.74) | 0.67 |
Abbreviations: BCVA, best-corrected visual acuity; CME, cystoid macular edema; CNV, choroidal neovascularization; cort, cortical; GLD, greatest linear diameter; LE, left eye; LS, letter score; NS, nuclear sclerotic; PSC, posterior subcapsular; PRN, pro-re nata; RE, right eye; SA, surface area; SD, standard deviation; SRF, subretinal fluid.
a
χ2-analysis used for comparison of gender, RE vs LE, cataract, SRF, and CME. One-way ANOVA used for comparison of age, CNV GLD, CNV SA, PED GLD, PED SA, PED height, and central 1-mm thickness; one-way ANOVA used for the comparison of contrast sensitivity; Kruskal–Wallis Test used for the comparison of VA.