Table 1.
Clinical data of patients analyzed in this study.
| Patient | Sex | Age at onset | Age at biopsy | CTG expansion | Myotonia | MIRS° | MRC# |
|---|---|---|---|---|---|---|---|
| CTR-1 | F | - | 43 | - | Not present | - | - |
| CTR-2 | M | - | 44 | - | Not present | - | - |
| CTR-3 | M | - | 48 | - | Not present | - | - |
| CTR-4 | F | - | 48 | - | Not present | - | - |
| DM1-1 | M | 38 | 39 | 370 | ± | 3 | 128.35 |
| DM1-2 | F | 35 | 45 | 460 | ++ | 4 | 128.35 |
| DM1-3 | M | 39 | 47 | 255 | + | 4 | 105.36 |
| DM2-1 | F | 35 | 51 | - | + | - | 118.70 |
| DM2-2 | F | 35 | 53 | - | ± | - | 132.99 |
| DM2-3 | F | 19 | 45 | - | ++ | - | 128.68 |
| DM2-4 | F | 54 | 59 | - | + | - | 109.68 |
°Muscle Impairment Rating Scale, stage of the disease for myotonic dystrophy type 1 (DM1) patients.53
#Medical Research Council, scale for muscle strength scale (0-5 grade) on 15 muscles at both sides in the upper and lower limbs for a total of 150 maximum score. CTR, control; DM1, myotonic dystrophy type 1; DM2, myotonic dystrophy type 2; F, female; M, male.