Table 1.
Morphmetric measurements of male and female mice.
Male mouse |
Female mouse |
|||||
---|---|---|---|---|---|---|
Wild-type | Mecp2stop/y | Mecp2stop/y, CreER | Wild-type | Mecp2+/stop | Mecp2+/stop, CreER | |
Femur weight (mg) | 51.90 ± 3.77 | 44.80 ± 3.41⁎, a | 51.80 ± 5.87⁎, b | 84.66 ± 9.47 | 79.50 ± 8.64 | 87.40 ± 6.99 |
Femur length (mm) | 13.78 ± 0.23 | 13.62 ± 0.22 | 13.70 ± 0.20 | 14.15 ± 0.57 | 13.45 ± 0.87 | 14.02 ± 0.02 |
Tibia weight (mg) | 55.50 ± 2.11 | 49.20 ± 1.21⁎⁎, a | 52.12 ± 2.96 | 68.84 ± 4.08 | 66.60 ± 2.98 | 68.80 ± 10.40 |
Tibia length (mm) | 17.66 ± 0.84 | 15.94 ± 0.48⁎⁎, a | 16.88 ± 0.51 | 16.33.0 ± 0.66 | 15.90 ± 1.52 | 15.31 ± 0.59 |
Average body weights (g) | 31.88 ± 3.85 | 28.14 ± 4.07 | 27.74 ± 2.68 | 32.72 ± 5.59 | 41.70 ± 7.15 | 39.47 ± 9.77 |
Bone weight and bodyweight measures in male and female cohorts. All data given as mean ± S.D. for each group of samples (n ≥ 5 per genotype). Significance was assessed by one way ANOVA with Tukey's post hoc test.
p < 0.05.
p < 0.01.
Comparison between Wt and Mecp2stop/y.
Comparison between Mecp2stop/y and Mecp2stop/y, CreER.