High and low anxious rats show similar acquisition of operant responding for cocaine and saccharin and a comparable saccharin intake. (a) High anxious (HA, n=12, dark gray circles) animals presented a similar number of daily cocaine infusions as compared with low anxious rats (LR, n=12, light pink triangles). (b) Furthermore, the two groups did not differ in their responding for saccharin and (c) consumed the same amount of sweetened solution.