Table 2. Biological Functions Over-represented in Differentially-expressed Gene Groups.
| Group comparisons | Numbers of biological groups at q<0.01 | Biological groups |
|---|---|---|
| (TO) MDD-NR/CTRL (Details in Supplementary Table S3) | 154 | Neutrophils: function, homing, chemotaxis, cell movement. Myeloid cells: response, cell movement, phagocytosis. Granulocytes: homing, chemotaxis, cell movement. Leukocytes: function, cell movement, migration, chemotaxis, quantity, proliferation. Phagocytes: phagocytosis, immune response, function, engulfment, homing, cell movement, response of Lymphocytes: proliferation. Immune Cells: proliferation, adhesion. Cells: chemotaxis, homing, immune response, phagocytosis Viral Infection, function of blood cells. Apoptosis of lymphoma cell lines, Inflammatory response. |
| (TO) MDD-NR/MDD-R (Details in Supplementary Table S4) | 12 | Viral Infection, replication of virus, replication of RNA virus, function of leukocytes, cell rolling of phagocytes, replication of Influenza A virus, function of neutrophils, cell death of myeloid cells, apoptosis of myeloid cells, infection of mammalia, immune response of cells, invasion of cells. |
| (TO) MDD-R/CTRL | 0 | None |
| (TO) CTRL(NR)/CTRL(R) | 0 | None |
| (T12) MDD-NR/CTRL | 0 | None |
| (T12) MDD-NR/MDD-R | 0 | None |
| (T12) MDD-R/CTRL | 0 | None |
| (T12) CTRL(NR)/CTRL(R) | 0 | None |
Significant biological groups defined using an ingenuity pathway analysis were regrouped and summarized by cell types. See Supplementary Table S4 for details.