Table 2. Areas Displaying Drug × Genotype Interactions During the Contrast Correct No-Go>Correct Odd (N=50).
Activated region |
MNI coordinates |
Cluster Size | BA | Z | Pcor | ||
---|---|---|---|---|---|---|---|
x | y | z | |||||
Cerebellum R | 12 | −44 | −14 | 7478 | — | 5.07 | <0.001 |
Occipital Pole L | −6 | −98 | 8 | 17 | 4.64 | ||
Intracalcarine Cortex R | 24 | −68 | 2 | 18/19 | 4.62 | ||
Cingulate Gyrus R | 4 | −8 | 40 | 1880 | 23 | 4.93 | <0.001 |
Cingulate Gyrus R | 0 | 4 | 36 | 4.73 | |||
Superior Frontal Gyrus R | 6 | 48 | 30 | 32 | 4.11 | ||
Supramarginal Gyrus R | 62 | −22 | 38 | 1046 | 1 | 4.54 | <0.001 |
Postcentral Gyrus R | 64 | −10 | 30 | 43 | 4.37 | ||
Parietal Operculum R | 48 | −26 | 22 | 48 | 4.09 | ||
Central Opercular Cortex R | 56 | 6 | 2 | 571 | 44 | 4.11 | 0.001 |
Insular Cortex R | 42 | 8 | 4 | 48 | 3.95 | ||
Inferior Frontal Gyrus R | 58 | 16 | 16 | 44 | 3.68 | ||
Middle Frontal Gyrus R | 36 | −2 | 54 | 541 | 6 | 4.50 | 0.001 |
Precentral Gyrus R | 38 | −14 | 58 | 6 | 4.01 | ||
Precentral Gyrus R | 30 | −6 | 48 | 6 | 3.99 | ||
Occipital Fusiform Gyrus R | 38 | −66 | −16 | 457 | 19 | 4.14 | 0.002 |
Middle Temporal Gyrus | 58 | −58 | −2 | 37 | 4.09 | ||
Middle Temporal Gyrus | 62 | −58 | 10 | 37 | 4.00 | ||
Temporal Pole R | 34 | 2 | −22 | 320 | 36 | 4.52 | 0.012 |
Temporal Pole R | 42 | 6 | 30 | 20 | 3.96 |
Abbreviations: BA, Brodmann area; FWEc, family-wise error corrected; L, left hemisphere, Pcor, p-value corrected; R, right hemisphere.
Note: Pcor for multiple comparison on the basis of cluster extent (FWEc; peak voxel threshold p<0.001 uncorrected). Anatomical regions from Harvard-Oxford Subcortical/Cortical Structural Atlas: L and R. Cluster size is given in number of voxels. Peak voxels are in italics, subclusters are indented.