Figure 6.

Maintenance of a low level of energy expenditure in SA-treated db/db mice. Diabetic db/db mice were treated with SA. (a) Food intake, (b) oxygen consumption (VO₂), (c) carbon dioxide output (VCO₂), (d) energy expenditure (EE), and (e) respiratory exchange ratio (RER) were measured by indirect calorimetry analysis for 72 h at 8 weeks of SA treatment (n = 7-8/group). ^* P < 0.05, ^** P < 0.01, and ^*** P < 0.005 compared with untreated mice; ^# P < 0.05, ^## P < 0.01 compared with the pair-fed group.