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. 2014 Dec 17;15(12):552. doi: 10.1186/s13059-014-0552-6

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© Leamy et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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QTL on Chr 9 show complex interactions with diet. (A-F) Plots of genotypic values at the QTL peak (X axis) are shown for six different OTUs that have peaks at the same or similar location on Chr 9 and which show differential effects depending on whether the G₁₀ mice were fed the control or the high-fat diet. Relative abundances of the OTUs for animals having the HR/HR parental, HR/B6 heterozygote, or B6/B6 parental genotypes at QTL peak are plotted on the Y-axis. (A) OTU17740. (B) OTU25269. (C) OTU25483. (D) OTU13989. (E) OTU29084. (F) OTU41353. Error bars based on standard error.