Table 6.
Geometric mean levels (and 95% confidence intervals) of liver enzymes by serum organochlorine pesticide exposure groups (1 = lowest, 4 = highest)
| Blood marker | Mirex | ||||
|---|---|---|---|---|---|
| n | 1 | 2 | 3 | 4 | |
| Aspartate aminotransferase AST (U/L) | 1951 | 23.2 (22.7, 23.6) | 23.7 (22.3, 25.3) | 24.3 (23.2, 25.5) | 25* (23.6, 26.5) |
| Gamma glutamyl transferase GGT (U/L) | 1951 | 18.8 (18.2, 19.4) | 22.2* (20.2, 24.4) | 22* (19, 25.3) | 19.7 (16.6, 23.2) |
| p,p’-DDE | |||||
| Alanine aminotransferase ALT (U/L) | 1956 | 20.9 (20, 21.8) | 22.9 (21.3, 24.5) | 22.7* (21.7, 23.7) | 22.5* (21.4, 23.6) |
| Gamma glutamyl transferase GGT (U/L) | 1956 | 19 (18, 20) | 21.1* (19.4, 22.9) | 19.7 (17.8, 21.7) | 18.9 (17.2, 20.7) |
| p,p’-DDT | |||||
| Alanine aminotransferase ALT (U/L) | 1965 | 20.4 (19.5, 21.3) | 23.3* (22, 24.7) | 22.8* (21.6, 24) | 22.6* (21.6, 23.7) |
| Aspartate aminotransferase AST (U/L) | 1965 | 22.6 (22, 23.2) | 24.1* (23.1, 25.3) | 23.8 (22.8, 24.7) | 24* (23.3, 24.7) |
| Gamma glutamyl transferase GGT (U/L) | 1965 | 18.1 (17, 19.2) | 20.7* (18.9, 22.6) | 20.3* (18.7, 22) | 19.8 (17.8, 21.9) |
| Trans-nonachlor | |||||
| Alanine aminotransferase ALT (U/L) | 1955 | 19.3 (17.9, 20.8) | 21 (20.2, 21.8) | 23.1*,# (22.1, 24.1) | 23.3*,# (21.9, 24.9) |
| Gamma glutamyl transferase (U/L) | 1955 | 15.4 (14.1, 16.9) | 19* (18, 20) | 20.4* (19, 21.9) | 21.3* (18.9, 24) |
| Oxychlordane | |||||
| Alanine aminotransferase ALT (U/L) | 1978 | 20.1 (19.2, 21.1) | 22* (20.9, 23.1) | 23.7* (22.5, 25) | 22† (20.7, 23.4) |
| Gamma glutamyl transferase GGT (U/L) | 1978 | 16.1 (14.6, 17.9) | 19.9* (18.6, 21.3) | 21.4* (19.6, 23.3) | 20.5* (18.2, 23.2) |
Comparisons are adjusted for age and gender. *p < 0.05 when compared to geometric mean of the first group; #p < 0.05 when compared to geometric mean of the second group; †p < 0.05 when compared to geometric mean of the third group.