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KRGE inhibited atheroma formation in aortic sinus. Mice were given normal chow diet (NCD), western diet (WD), and WD supplemented with KRGE for 13 weeks. Fixed aortic sinuses were stained with H&E. (a) NCD-fed wild type mice, (b) NCD-fed LDLr−/− mice, and ((c) and (d)) WD-fed LDLr−/− mice with 50 mg/kg/day (e) or 200 mg/kg/day (f) of KRGE. The dotted area exhibits lipid deposition in the aorta.
