[Table/Fig-1]:
Comparison of parameters among study groups
| 1st Trimester (Group I) (n=20) | 2nd Trimester (Group II) (n=20) | 3rd Trimester (Group III) (n=20) | Controls (n=30) | ||
|---|---|---|---|---|---|
| POG (weeks) | Mean±SD | 10.4±0.82 | 16.35±0.93 | 34.35±2.76 | - |
| Age (years) | Mean±SD | 22.6±2.60 | 22.45±1.82 | 22.05±3.52 | 22.83±2.98 |
| t test (p)* | 0.771 | 0.576 | 0.283 | - | |
| Fasting Plasma Glucose (mg/dl) | Mean±SD | 81.59±7.31 | 82.26±9.65 | 79.52±13.41 | 81.34±5.31 |
| t test (p)* | 0.898 | 0.704 | 0.569 | - | |
| Fasting S. Insulin (μIU/ml) | Mean±SD | 6.50±1.56 | 7.81±2.41 | 9.68±2.76 | 6.01±1.95 |
| t test (p)* | 0.336 | < 0.05† | < 0.001‡ | - | |
| FGIR | Mean±SD | 13.25±3.27 | 11.98±5.65 | 8.95±3.52 | 14.97±5.14 |
| t test (p)* | 0.155 | 0.065 | < 0.001‡ | - | |
| QUICKI | Mean±SD | 0.369±0.016 | 0.361±0.025 | 0.350±0.021 | 0.376±0.02 |
| t test (p)* | 0.229 | < 0.05† | < 0.001‡ | - | |
| log (Fasting S. Insulin) | Mean±SD | 0.8±0.11 | 0.87±0.16 | 0.97±0.14 | 0.76±0.14 |
| t test (p)* | 0.225 | < 0.05† | < 0.001‡ | - | |
| log (HOMA 1-IR) | Mean±SD | 0.1±0.12 | 0.17±0.18 | 0.26±0.16 | 0.06±0.14 |
| 0.249 | < 0.05† | < 0.001‡ | - |
* p-value of unpaired student’s t-test between respective case groups and controls., POG – period of gestation; HOMA1-IR – Homeostatic Model Assessment for IR., † Significant, ‡ Highly Significant