Table 4.
Change in lipid profile during the six months of intervention and the follow up in each group
| Variables | Ctrl/Spi | Period | Patients received local balance diet | Patients received spirulina combined with a local balance diet | P-value |
|---|---|---|---|---|---|
| Total cholesterol (mg/dL) | 87/82 | T0 | 194.8 ± 80.1 | 228.7 ± 96.8 | 0.17 |
| 79/80 | T6 | 216.8 ± 109.4 | 143.3 ± 45.4 | <0.001 | |
| 66/79 | T12 | 234.9 ± 101.8 | 141.4 ± 40.1 | <0001 | |
| HDL cholesterol (mg/dL) | 87/82 | T0 | 53.6 ± 18.4 | 48.0 ± 21.1 | 0.71 |
| 79/80 | T6 | 49.9 ± 21.6 | 83.2 ± 39.7 | <0. 001 | |
| 88/79 | T12 | 57.3 ± 27.0 | 100.9 ± 28.7 | <0.001 | |
| LDL cholesterol (mg/dL) | 87/82 | T0 | 120.12 ± 75.8 | 127.0 ± 92.2 | 0.60 |
| 79/80 | T6 | 138.3 ± 105.8 | 44.5 ± 33.0 | <0.001 | |
| 66/79 | T12 | 146.3 ± 97.8 | 29.3 ± 16.8 | <0.001 | |
| Triglycerides (mg/dL) | 87/82 | T0 | 117.6 ± 76.8 | 206.9 ± 122.7 | <0.0001 |
| 79/80 | T6 | 150.4 ± 97.5 | 139.8 ± 64.2 | 0.44 | |
| 66/79 | T12 | 167.1 ± 124.8 | 123.5 ± 44.6 | <0.01 | |
| CT/HDL (mg/dL) | 87/82 | T0 | 3.6 ± 4.3 | 4.7 ± 4.6 | 0.21 |
| 79/80 | T6 | 4.34 ± 5.1 | 1.7 ± 1.1 | 0.64 | |
| 66/79 | T12 | 4.1 ± 3.0 | 1.4 ± 1.4 | <0.0001 | |
| LDL/HDL (mg/dL) | 87/82 | T0 | 2.2 ± 4.1 | 2.6 ± 4.3 | 0.26 |
| 79/80 | T6 | 2.8 ± 4.89 | 0.53 ± 0.84 | 0.21 | |
| 66/79 | T12 | 2.5 ± 3.6 | 0.3 ± 0.6 | <0.0001 |
Mean values ± SD.
Ctrl: Control, Spi: Spirulina group; TC: HDL-C and LDL-C: HDL-C ratios were used to calculate the atherogenicity index. TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TG, triglycerides, P < 0.01: Significant difference between the group.