Figure 5.

Genetic interactions for mitochondria dysfunction in schizophrenic candidate genes. This figure illustrates the genetic interaction network for mitochondrial associated genes and schizophrenic candidate genes. The blue nodes located inside the mitochondria denoted the under-expressed schizophrenic candidate genes from Wu et al. Red and green nodes located outside from mitochondria(except NDUFB11) represent over and under-expressed candidate genes from this study. NDUFB11 was found in both candidate genes from Wu et al. and this study. It indicates the mitochondrial associated under-expressed candidate genes manifested by mitochondrial dysfunction may contribute to the susceptibility of negative symptom for schizophrenia.