Table 2.
Timing of earliest differentiation of the studied peptidergic cell types within particular hypothalamic progenitor areas.
| Terminal areas | E10.5 | E11.5 | E12.5 | E13.5 | E15.5 | E.18.5 | |
|---|---|---|---|---|---|---|---|
| TPa | TPaD | ||||||
| TPaC | Oxt | Gal | |||||
| TPaV |
Trh Ghrh |
Cartp; Sst |
Avp | Penk | |||
| TSPa | TSPa | Cartpt |
Vip Avp? Oxt? (SCH) |
||||
| Tu | TuD (ABas) |
Sst | Pomc |
Cartpt Npy Penk |
|||
| TuI |
Ghrh (Arc) Npy (Arc) Pdyn (VM) |
Agrp (Arc) |
Gal (DM-T) |
||||
| TuV | |||||||
| PM | PM | Pmch |
Penk Gal Sst |
||||
| M | M | ||||||
| Peduncular areas | E10.5 | E11.5 | E12.5 | E13.5 | E15.5 | E.18.5 | |
| PPa | DPa | ||||||
| CPa | Crh |
Oxt Gal |
|||||
| VPa |
Trh Ghrh |
Cartpt | Sst |
Avp Penk Pdyn |
|||
| PSPa | |||||||
| RTu | RTuD (PBas) |
Pmch |
Penk Npy Sst |
Hcrt | |||
| RTuI (DM-P) |
Gal Pdyn |
||||||
| RTuV | |||||||
| PRM | PRM |
Npy Pmch Sst |
Penk | ||||
| RM | RM |
Light gray areas are devoid of peptidergic cells, whereas dark gray areas produce two or more types simultaneously. Orange background: Alar domains. Reddish background: Basal domains. Bold letters: peptidergic cells studied in Morales-Delgado et al., 2011; Morales-Delgado et al., 2014; Morales-Delgado, 2012. All other peptidergic cell types were analyzed from Allen Developing Mouse Brain Atlas datasets.