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. 2014 Dec 1;171(24):5682–5695. doi: 10.1111/bph.12870

Figure 6.

Figure 6

Effects of ETA and ETB receptor antagonists on the ET-1-elicited blunting of ACh-induced relaxation of penile arteries from LZR and OZR. (A, B) Effects of ET-1 (0.3 nM) and the ETA receptor antagonist BQ123 (1 μM) on the relaxant responses elicited by ACh in penile arteries from LZR (A) and OZR (B). (C, D) Average effects of ET-1 and of the ETB receptor antagonist BQ788 (0.1 μM) on the relaxant responses to ACh in penile arteries from LZR (C) and OZR (D). Results are means ± SEM of n = 3–5 animals (one to two arteries from each animal). *P < 0.05 versus control Emax, †P < 0.05 versus ET-1-treated Emax; Student's t-test for unpaired observations.